Glutamate receptors phd program

Moody, L. Wollmuth , and H. Brain Research. Jun 1; Zoodsma, J. Bhandiwad, D. Golann, G. Liu, S. Syed, A. Napoli, H. Burgess, H. The Journal of Neuroscience. Chan, K. Huerta, N.

Certain, G. Moody, C. Kowal, P. Huerta, B. Volpe, B. Nature Communications , Vaithianathan, T, L. Wollmuth , D. Henry, D. Zenisek, and G. Matthews Tracking newly released synaptic vesicle proteins at the active zones of ribbon synapses. Esmenjaud, J. Stroebel, K. Chan, T. Grand, M. David, L. Wollmuth , A. The main focus of my laboratory is directed toward understanding the genetic basis of emotion.

We are particularly interested in the limbic system of the brain which is critical for determining where we are, where we have been, what we are doing, what we plan to do, and how all of it makes us feel. We are currently investigating how a small group of neurons located in the ventral midbrain that synthesize and release the neurotransmitter dopamine influence activity patterns within the limbic system to direct behavior. Dopamine release into target brain regions can either be tonic low steady levels of neurotransmitter or phasic transient high concentrations of neurotransmitter , and these patterns are thought to play distinct roles in modulating the function of the limbic system.

Krall, R. Phillips, M. Interplay between gating and block of ligand-gated ion channels. Brain Sci. Leiva, R. Pharmacological and electrophysiological characterization of novel NMDA receptor antagonists. ACS Chem. Glasgow, N. Memantine and ketamine differentially alter NMDA receptor desensitization. Mesbahi-Vasey, S. All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water.